ISOLATION OF ALKALOIDS FROM CULTURED HYBRID CELLS OF RAUWOLFIA SERPENTINA x RHAZYA STRICTA

Norio AIMI; Mariko KITAJIMA; Naoko OYA; Wataru NITTA; Hiromitsu TAKAYAMA; Shin-ichiro SAKAI; Igor KOSTENYUK; Yuri GLEBA; Susanne ENDREB; Joachim STOCKIGT

doi:10.1248/cpb.44.1637

Norio AIMI, Mariko KITAJIMA, Naoko OYA, Wataru NITTA, Hiromitsu TAKAYAMA, Shin-ichiro SAKAI, Igor KOSTENYUK, Yuri GLEBA, Susanne ENDREB, Joachim STOCKIGT

Author information

Norio AIMI
Mariko KITAJIMA
Naoko OYA
Wataru NITTA
Hiromitsu TAKAYAMA
Shin-ichiro SAKAI
Igor KOSTENYUK
Yuri GLEBA
Susanne ENDREB
Joachim STOCKIGT
Author's Organization：
Faculty of Pharmaceutical Sciences, Chiba University
Faculty of Pharmaceutical Sciences, Chiba University
Faculty of Pharmaceutical Sciences, Chiba University
Faculty of Pharmaceutical Sciences, Chiba University
Faculty of Pharmaceutical Sciences, Chiba University
Faculty of Pharmaceutical Sciences, Chiba University
Institute of Cell Biology and Genetic Engineering, Ukr. Academy of Sciences
Institute of Cell Biology and Genetic Engineering, Ukr. Academy of Sciences
Institute of Pharmacy, Johannes Gutenberg-Universitat Mainz
Institute of Pharmacy, Johannes Gutenberg-Universitat Mainz

Keywords: hybrid cell, Rauwolfia serpentina, Rhazya stricta, Apocynaceae, indole alkaloid

JOURNAL FREE ACCESS

1996 Volume 44 Issue 8 Pages 1637-1639

DOI https://doi.org/10.1248/cpb.44.1637

Details

Abstract

Two monoterpenoid indole alkaloids and four β-carbolines were isolated from a hydrid cell suspension culture generated from two Apocynaceous plants, Rauwolfia serpentina Benth. and Rhazya stricta Decaisne. This indicates that the function of alkoloid biosynthesis is retained after hybrid formation and that alkaloids not previously detected in the parental plants or cell cultures are formed.

Corresponding author

Register with J-STAGE for free!