Studies on Kochiae Fructus. II. On the Saponin Constituents from the Fruit of Chinese Kochia scoparia (Chenopodiaceae) : Chemical Structures of Kochianosides I, II, III, and IV

Abstract

Four new saponins called kochianosides I, II, III, and IV were isolated from the glycosidic fraction of the fruit of Chinese Kochia scoparia, which has exhibited an antipruritogenic effect, together with eight known saponins. The structures of kochianosides I, II, III, and IV were characterized on the basis of physicochemical evidence as 22α-hydroxyoleanolic acid 3-O-β-D-glucopyranosiduronic acid, morolic acid 3-O-[β-D-glucopyrabnosyl(1→2)][β-D-xylopyranosyl(1→3) -β-D-glucopyranosiduronic acid, 3β, 12α-dihydroxyolean-28, 13β-olide 3-O-β-D-xylopyranosyl(1→3)-β-D-glucopyranosiduronic acid, and betulinic acid 3-O-β-D-xylopyranosyl(1→3)-β-D-glucopyranosiduronic acid, respectively.