Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Taxuspines X-Z, New Taxoids from Japanese Yew Taxus cuspidata
Hideyuki SHIGEMORIXiao-Xia WANGNaotoshi YOSHIDAJun'ichi KOBAYASHI
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1997 Volume 45 Issue 7 Pages 1205-1208

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Abstract
Three new taxoids, taxuspines X-Z (1-3), have been isolated from stems of the Japanese yew Taxus cuspidata SIEB. et ZUCC. ant the structures elucidated on the basis of spectroscopic data. Taxuspine X (1) is a rare example of a bicyclic taxane-related diterpenoid consisting of 6/12-memebered ring system with a cinnamoyl group at C-5. Taxuspine Y (2) is one of unique taxoids with 5/7/6-membered ring system, while taxuspine Z (3) is a new taxoid consisting of 6/8/6-ring system with a Winterstein's acid moiety at C-5.
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© The Pharmaceutical Society of Japan
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