Studies on the Constituents of Brazilian Propolis

Abstract

Two new cinnamic acid derivatives along with twenty two known compounds, including five flavoniods, three phenolic compounds, six caffeoylquinic acids and eight cinnamic acid derivatives, were isolated from Brazilian propolis. New compounds were elucidated as (E)-3-(2, 2-dimethyl-3, 4-dihydro-3-hydroxy-8-prenyl-2H-1-benzo pyran-6-yl)-2-propenoic acid and (E)-3-[2, 3-dihydro-2-(1-hydroxy-1-methylethyl)-7-prenyl-benzofuran-5-yl]-2-propenoic acid, on the basis of spectral evidence. Three compounds; dihydrokaempferide, (+)-threo-1-C-guaia-cylglycerol and 3-prenyl 4-(2-methylpropionyloxy)cinnamic acid were isolated from propolis as the first time.