1958 Volume 6 Issue 5 Pages 487-490
5-Dialkylamino-1, 3, 6-trialkyluracils, which were analogous with aminopyrine in chemical structure, were synthesized systematically and their phamacological actions were investigated. It is interesting that 5-dimethylamino-3-cyclohexyl-1, 6-dimethyluracil (V) showed analgesic, hypothermic, antifebrile, and moreover tranquilizing actions with less toxicity than aminopyrine.