On the Nitration of Quinoxalines.

Abstract

Quinoxaline, quinoxaline N-oxide, and 2, 3-dimethylquinoxaline were resistant to nitration, but the quinoxaline derivatives containing polar functions, either in benzene or pyrazine ring, were readily nitrated. Thus, 5-methoxy-, 6-methoxy-, and 2-hydroxy-3-methyl-quinoxalines yielded upon nitration 5-methoxy-6, 8-dinitro-, 5-nitro-6-methoxy-and 2-hydroxy-3-methyl-6-nitro-quinoxalines, respectively.