Metabolism of Flavin Nucleotides. I. Decomposition of Flavin Nucleotides in Digestive Juice.

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Decomposition of flavin nucleotides in digestive juices was studied. 1. Free riboflavin, FMN, and FAD were not decomposed in saliva. 2. In gastric juice, about 20% of FAD was decomposed to FMN by the hydrochloric acid in gastric juice during 3 hours'incubation at 37° while free ribofiavin and FMN were not decomposed. 3. In bile, 10% of FMN was decomposed to free riboflavin during 2 hours' incubation, free riboflavin and FAD were not decomposed. 4. In pancreatic juice, 45% of FMN was decomposed to free riboflavin during 2 hours' incubation, but free riboflavin and FAD were not decomposed.