Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on the Metabolism of Naturally Occurring Coumarins. IV. Urinary Metabolites of Dimethylesculetin and Scopoletin.
古谷 力
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1958 年 6 巻 6 号 p. 696-700

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Dimethylesculetin was demethylated in the rabbit to give esculetin 7-methyl ether, scopoletin, and esculetin. The free and conjugated forms of each metabolite were determined directly by a densitometer applied on the paper chromatogram. The urinary metabolites obtained from scopoletin have also been examined.

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© The Pharmaceutical Society of Japan
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