Studies on Acylase Activity and Microorganisms. XII. Optical Resolution of Glutamic and Aspartic Acids by Metabolism of Soil Bacteria on Benzoyl Derivatives of DL-Amino Acids

Abstract

The metabolic activities of 4 strains (KT-230, KT-231, KT-232, and KT-233) of soil bacteria were tested on glutamic and aspartic acids and their benzoyl derivatives, and it was found that benzoyl-DL-glutamic and benzoyl-DL-aspartic acids are resolved by the metabolism of KT-230 and KT-231, but not by KT-232 and KT-233. It was also demonstrated that KT-231 metabolized benzoyl-DL-glutamic and benzoyl-DL-aspartic acids to yield L-amino acids and the corresponding benzoyl-D-amino acids.