Author's Organization：Pharmaceutical Institute, Medical Faculty, University, of Kyoto, and Gifu College of Pharmacy Pharmaceutical Institute, Medical Faculty, University, of Kyoto, and Gifu College of Pharmacy Pharmaceutical Institute, Medical Faculty, University, of Kyoto, and Gifu College of Pharmacy
A new synthetic route for N, N-dimethyl-1-m-hydroxyphenylcyclohexaneethylamine (IX) from ethyl cyclohexylidenecyanoacetate is described. 1-(m-Methoxyphenylcyclohexyl) trimethylamine (XII) was prepared by the Curtius degradation of 1-m-methoxyphenyl-cyclohexaneacetic acid (V) and subsequent dimethylation.
