Steroid Studies. XVIII. Reduction of 5, 7-Diene in 10-Isosteroid

Abstract

The behavior of the double bond in the various derivatives of 4, 4-dimethyl-10-isocholesta-5, 7-dien-3β-ol (II) to reduction with sodium and ethanol or over Raney nickel catalyst was comparatively examined with that of 10-normal steroid. It was thereby found that the double bond at 7-position in the iso series is easily reduced by catalytic reduction over Raney nickel.