Studies on Carcinostatic Substances. XXVII. Anti-tumor Activity of 2-Chloroethylamine Derivatives on the in vitro-Cultured Yoshida Sarcoma Cells

Abstract

More than 200 derivatives of 2-chloroethylamine were tested as to their anti-tumor effect on the in vitro-cultured Yoshida sarcoma cells. The results were discussed, especially in connection with conditions of activation of N-methyl-bis(2-chloroethyl)amine N-oxide by the tumor cells.