Studies on the Metabolism of Naturally Occurring Anthraquinones. II. The Metabolism of 1-Methoxyanthraquinone and 2-Methoxyanthraquinone.

Abstract

Each of 1-methoxy-and 2-methoxyanthraquinones was demethylated in rats to be metabolized to the 1-hydroxy compound and they were finally hydroxylated to alizarin. Every form in conjugation of their metabolites was determined using a densitometer and an ultraviolet spectrophotometer.