Protection by Cepharanthie of the Mitochondrial Function from Damage Induced by Snake Venom, Phospholipase A2, Lysolecithin and Lead

Masanobu Miyahara; Kaname Aono; Jorge Sancho Queseda; Kunio Shimono; Yuji Baba; Syoichi Yamashita

doi:10.1247/csf.3.61

Protection by Cepharanthie of the Mitochondrial Function from Damage Induced by Snake Venom, Phospholipase A₂, Lysolecithin and Lead

Masanobu Miyahara, Kaname Aono, Jorge Sancho Queseda, Kunio Shimono, Yuji Baba, Syoichi Yamashita

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JOURNAL FREE ACCESS

1978 Volume 3 Issue 1 Pages 61-65

DOI https://doi.org/10.1247/csf.3.61

[Correction] Cell Structure and Function Vol.3 No.2 (1978) pp.e1-e1

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Abstract

The action of cepharanthie, a biscoclaurine alkaloid, on disturbances of the mitochondrial function caused by snake venom, phospholipase A₂, lysolecithin, lead and high temperature was examined. The alkaloid protected mitochondria from damage caused by these treatments. The results suggest that the alkaloid protects biomembranes from various damage with no effect of its own at a low concentration.

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