Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Development of Innovative Diagnosis and Therapeutic Systems based on Nanobiotechnology” Editor : Kazunori Kataoka
Clinical development of nano-DDS
Yasuhiro Matsumura
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Keywords: DDS, EPR effect, liposome, micelle, CAST
JOURNAL FREE ACCESS

2011 Volume 26 Issue 1 Pages 20-28

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Abstract
Anticancer agents categorized in DDS based on nanotechnology have been approved. Regarding a pipeline of clinical development of micelle carrier system, total 6 clinical trials are now underway not only in Japan but also in other countries.
In this chapter, clinical status of other formulations of DDS as well as micelle carriers will be described. In addition, cancer stromal targeting therapy recently proposed by us will be discussed.
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© 2011 Japan Society of Drug Delivery System
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