119 巻 (2009) 8 号 p. 1515-1534
Standard guideline for management (diagnosis, severity scoring and therapy) of atopic dermatitis (AD) is established. In this guideline, the necessity of dermatological training is emphasized in order to assure the diagnostic skill and to enable to evaluate the severity of AD. The present standard therapies for AD consist of the use of topical steroids and tacrolimus ointment for inflammation as well as emollients for dry and barrier-disrupted skin as the first-line topical applications, systemic anti-histamines and anti-allergic drugs for pruritus, avoidance of apparent exacerbating factors, psychological counseling, and advice about daily life. Tacrolimus ointment (0.1%) and its low density ointment (0.03%) are available for adult patients and 2-15 year old patients, respectively. The importance of correct selection of topical steroids according to the severity of the lesion is also emphasized. Deliberate use of oral cyclosporine for severe recalcitrant adult AD is also referred.