グリシン過剰投与の影響について (第2報)
グリシン過剰投与と尿中クレアチニンおよびアミノ酸について
1964 年 22 巻 6 号 p. 193-197
詳細
1964 年 22 巻 6 号 p. 193-197
To see the effect of Excess glycine on the urinary amino acids, free and conjugated form glycine and methionine were investigated by microbioassay method. The fractions of free amino acids were obtained by high voltage paper electrophoresis method. Creatinine in urine was also determined.
According to the results, creatinine in urine increased by the excess glycine, and a little more increment was seen by the addition of 0.25% DL-methionine. Free glycine in urine increased greatly by the addition of 5% glycine, but the addition of 0.25% DL-methionine lowered the free glycine excretion in urine.
On the other hand, conjugated form glycine also increased when fed 5% glycine diet, and higher increment was appeared by adding 0.25% DL-methionine as seen on Group 4.
Free and conjugated form methionine in urine decreased greatly by the addition of 5% glycine.
From the figures of free amino acids in urine which were obtained by high voltage paper electrophoresis, an increment of the fractions of basic amino acids were recognized by the addition of 5% glycine in the diet.
