2005 年 63 巻 6 号 p. 357-362
This study on the link between urinary amino acid and food intake was undertaken as one of the objectives of the Hyogo Prefecture Health Promotion Association. 90 women aged 58-78 years consented to the health examination required for this study. The subjects were classified as inhabitants of three types of area in Hyogo: city, inland, and seaside. Twenty-four hour urine was collected, and the taurine, 1-methylhistidine (1-MH) and 3-methylhistidine (3-MH) levels were measured. The results show that the level of taurine in the seaside group was significantly higher than that in the city group (p<0.05), and that the 1-MH level in the city group was significantly higher than that in the seaside group (p<0.01). The 3-MH level in the seaside group was significantly higher than that in the inland (p<0.05) and the city groups (p<0.01). Those in the seaside group eating seafood 3 to 5 times per week had a significantly higher urinary taurine level (p<0.05), while those in the city group eating meat 3 to 5 times per week had a significantly higher urinary 1-MH level than the subjects in the other areas (p<0.01). The urinary 3-MH levels were similar in the three areas, and there was a positive correlation (r=0.43) between the taurine and 3-MH levels. It is concluded that the 3-MH level was related to the consumption of animal protein, including seafood and shellfish.