The relationship between serum thyrotropin and components of metabolic syndrome

Yaxin Lai; Jiani Wang; Fengwei Jiang; Beibei Wang; Yanyan Chen; Mengchun Li; He Liu; Chenyan Li; Haibo Xue; Ningna Li; Jiashu Yu; Liangfeng Shi; Xue Bai; Xin Hou; Lin Zhu; Li Lu; Sen Wang; Qian Xing; Xiaochun Teng; Weiping Teng; Zhongyan Shan

doi:10.1507/endocrj.K10E-272

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The relationship between serum thyrotropin and components of metabolic syndrome

Yaxin Lai, Jiani Wang, Fengwei Jiang, Beibei Wang, Yanyan Chen, Mengchun Li, He Liu, Chenyan Li, Haibo Xue, Ningna Li, Jiashu Yu, Liangfeng Shi, Xue Bai, Xin Hou, Lin Zhu, Li Lu, Sen Wang, Qian Xing, Xiaochun Teng, Weiping Teng, Zhongyan Shan

著者情報

Yaxin Lai
Department of Endocrinology and Metabolism, The First Hospital of China Medical University, Shenyang, China
Jiani Wang
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Fengwei Jiang
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Beibei Wang
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Yanyan Chen
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Mengchun Li
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
He Liu
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Chenyan Li
Department of Endocrinology and Metabolism, The First Hospital of China Medical University, Shenyang, China
Haibo Xue
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Ningna Li
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Jiashu Yu
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Liangfeng Shi
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Xue Bai
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Xin Hou
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Lin Zhu
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Li Lu
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Sen Wang
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Qian Xing
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Xiaochun Teng
Department of Endocrinology and Metabolism, The First Hospital of China Medical University, Shenyang, China
Weiping Teng
The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China
Zhongyan Shan
Department of Endocrinology and Metabolism, The First Hospital of China Medical University, Shenyang, China

キーワード: Metabolic syndrome, Thyrotropin, Subclinical hypothyroidism, Subclinical hyperthyroidism

ジャーナルフリー早期公開

論文ID: K10E-272

DOI https://doi.org/10.1507/endocrj.K10E-272

この記事には本公開記事があります。

The final version of this article is now available: Vol. 58 (2011) , No. 1 p.23

詳細

抄録

To explore the relationship between serum thyrotropin and components of metabolic syndrome in a Chinese cohort. A total of 1534 adult inhabitants in DaDong district of Shenyang were asked to fulfill the questionnaire, complete physical examination and OGTT. Blood samples were collected to test thyrotropin (TSH), fasting plasma glucose (FPG), OGTT 2h PG, fasting insulin (FINS), triglyceride (TG) and high density lipoprotein cholesterol (HDL-C). Serum TSH in metabolic syndrome group was higher than that in the non-metabolic syndrome group (2.54 mIU/L vs. 2.22 mIU/L, p<0.05). TG level increased significantly in subclinical hypothyroid group compared with euthyroid subjects (1.73±0.12 mmol/L vs.1.47±0.03 mmol/L, p<0.05), and HDL-C decreased significantly in patients with subclinical hypothyroidism compared with euthyroid subjects (1.26±0.27 mmol/L vs. 1.33±0.27 mmol/L, p<0.05). The prevalence of hypertension was higher in the subclinical hypothyroid group than that in euthyroid group (42.86% vs. 33.2%, p<0.05). The serum TSH within the reference range was positively related with the prevalence of overweight/obesity. Slight increase in serum TSH maybe a risk factor for metabolic syndrome.

責任著者(Corresponding author)

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