抄録
1. As a stress response, the pituitary-gonadal system is activated by the endogenous release of oxytocin, and even in the narcosis with chlorpromazine, oxytocin, endogenously or exogenously, increases the urinary excretion of gonadotrophin and 17-ketosteroids, especially the gonadal fractions and brings about the corresponding cellular changes in the adenohypophysis and gonads.
2. An exogenous administration of acetylcholine raises the liberation of oxytocin from the hypothalamic neurosecretory system without suffering from any inhibitory effect of chlorpromazine and promethazine.
3. The effect of the exogenous injection of acetylcholine on the pituitary-gonadal system is just the same as that of oxytocin.
4. Some discussions are made on the concept on the role of the hypothalamicpituitary neurosecretion, in regard to the secretion of the adenohypophysis in the natural stress response.
