Adrenal Insufficiency in a Patient with Acquired Immunodeficiency Syndrome

KOICHI FUJII; ISAO MORIMOTO; ATSUSHI WAKE; YOHSUKE OKADA; NOBUO INOKUCHI; OSAMU ISHIDA; YOICHIRO NAKANO; SUSUMU ODA; SUMIYA ETO

doi:10.1507/endocrj.41.13

KOICHI FUJII, ISAO MORIMOTO, ATSUSHI WAKE, YOHSUKE OKADA, NOBUO INOKUCHI, OSAMU ISHIDA, YOICHIRO NAKANO, SUSUMU ODA, SUMIYA ETO

著者情報

KOICHI FUJII
First Department of Internal Medicine, University of Occupational and Environmental Health
ISAO MORIMOTO
First Department of Internal Medicine, University of Occupational and Environmental Health
ATSUSHI WAKE
First Department of Internal Medicine, University of Occupational and Environmental Health
YOHSUKE OKADA
First Department of Internal Medicine, University of Occupational and Environmental Health
NOBUO INOKUCHI
First Department of Internal Medicine, University of Occupational and Environmental Health
OSAMU ISHIDA
First Department of Internal Medicine, University of Occupational and Environmental Health
YOICHIRO NAKANO
First Department of Internal Medicine, University of Occupational and Environmental Health
SUSUMU ODA
First Department of Internal Medicine, University of Occupational and Environmental Health
SUMIYA ETO
First Department of Internal Medicine, University of Occupational and Environmental Health

キーワード: Acquired Immunodeficiency Syndrome (AIDS), Cytomegalovirus infection, Adrenal Insufficiency, Addison's Disease

ジャーナルフリー

1994 年 41 巻 1 号 p. 13-18

DOI https://doi.org/10.1507/endocrj.41.13

詳細

抄録

A 46-year-old man was admitted because of hypotension and consciousness disturbance. He was a patient with hemophilia B, and diagnosed as having an AIDS- related complex 2 years prior to admission. On admission he had severe hyponatremia. Hormonal studies revealed that he had Addison's disease. Serum cytomegalovirus (CMV) antibody titers were high, and a CMV antigen was detected in his urine, which suggested CMV adrenalitis caused by an active CMV infection. After the administration of hydrocortisone and ganciclovir, his general clinical condition and biochemical test results were back to normal. However, the adrenal dysfunction was irreversible, despite the treatment with ganciclovir. With an increase in the number of AIDS patients, we have to consider adrenal insufficiency due to a CMV infection in patients with AIDS.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）