家兎に於けるSantoninの排泄に關する研究
第2報 家兎に於ける尿中の未變化Santonin排泄量と肝臓機能との關係に就て
1952 年 48 巻 4 号 p. 244-247,en27
詳細
1952 年 48 巻 4 号 p. 244-247,en27
The influence of liver function on the urinary excretion of unchanged santonin was investigated in rabbits. The results obtained were as follows. After the liver was damaged by CCl4 the urinary excretion of santonin increased markedly over the control ; it was decreased when the function of liver was stimulated by dehydrocholic acid or sodium thiosulphate. These results showed conversely the same relation that oxysantonin was excret. ed in the urine proportionally to the function of liver, and it was accordingly considered that santonin would be changed to oxysantonin in liver.
