抄録
Liquid seasoning was prepared from the wash water produced during cod surimi production, which is normally discarded, using an hydrolysis test plant. This solution had not only a good flavor but also showed inhibitory activity on the angiotensin I-converting enzyme (ACE). Inhibitors in the liquid seasoning showed a molecular weight distribution of about 200 to 500 by gel filtration chromatography. Two inhibitory peptides were isolated from the liquid seasoning using reverse-phase HPLC. The amino acid sequences of inhibitory peptides were Val-Trp and Ile-Trp. Peptide sequences of Val-Trp and Ile-Trp were found in the primary structure of actin. Val-Trp fragment exists also in myoglobin.
