痛風と尿酸・核酸
Online ISSN : 2435-0095
原著 5
Monosodium Urate Crystal Deposition and Gout Flare History in Hyperuricemia
Hiroshi KataokaMika NakanowatariTomoko TomitaMakoto KondoMasaya Mukai
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2021 年 45 巻 2 号 p. 155-160

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Objective: To investigate the frequency and findings of monosodium urate (MSU) deposition in gout flares compared to those in asymptomatic hyperuricemia.

Methods: A total of 109 consecutive patients with gout or asymptomatic hyperuricemia who visited our clinic between 2017 and 2020 were enrolled in this study. The inflamed joints of patients with gout and one of the two metatarsophalangeal joints of patients with asymptomatic hyperuricemia were examined for MSU deposition on ultrasonography. We investigated whether imaging findings were related to the history of gout flares and comorbidities of the patients.

Results: A total of 52 patients were eligible for this study. The patients with gout were older than the asymptomatic patients. All patients with gout showed the double contour sign and a hyperechoic aggregate representing MSU deposition, whereas three of the 15 patients with asymptomatic hyperuricemia had any of these ultrasonography signs. There was no relationship between comorbidities and gout flares.

Conclusions: The presence of MSU deposition on ultrasonography indicated a history of gout flare, and it rarely occurred in patients with asymptomatic hyperuricemia.

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© 2021 Japanese Society of Gout and Uric & Nucleic Acids
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