レプラ
Online ISSN : 2185-1352
Print ISSN : 0024-1008
ISSN-L : 0024-1008
鼠癩感染機転に関する研究
第2篇抗単球家兎免疫血清の鼠癩に及ぼす影響
鈴木 正和
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ジャーナル フリー

1959 年 28 巻 6 号 p. 324-330

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抄録
One hundred and twenty-six rats were used in this experiment. The author employed the anti-monocyte serum obtained from rabbits which were sensitized by intraperitoneal monocyte of rats.
The host cells of murine leprosy bacilli were injuried by reversed-allergic reaction caused by this serum. In intraperitoneally inoculated murine leprosy, multiplication of murine leprosy bacilli in the intraperitoneal monocyte of the group was inhibited markedly as compared with control group and the bacilli left early the cells.
In autopsy cases after 40 days of each group, development of leproma was inhibited markedly in the group. After five months the autopsy showed the inhibition of the dissemination of bacilli. Exceptionally, in a group which injected with liquid paraffin before the injection of serum, multiplication of murine leprosy bacilli was inhibited as compared with untreated group.
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© 日本癩学会
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