Drug delivery systems (DDS) that deliver drugs selectively and efficiently to target sites can be made more effective by using ultrasound. However, ultrasound DDS has a problem of low drug release rate. In this study, we propose liposomes encapsulating metal nanoparticles as a new drug carrier with enhanced responsiveness to ultrasound stimulation. We report the results of microscopic observations of changes in brightness values within liposomes to confirm the improvement in ultrasound response.
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