Industrial Health
Online ISSN : 1880-8026
Print ISSN : 0019-8366
ISSN-L : 0019-8366
SYNERGISTIC RESPONSE OF HYDROGEN PEROXIDE AEROSOLS AND SULFUR DIOXIDE TO PULMONARY AIRWAY RESISTANCE
Toshio TOYAMAKenichi NAKAMURA
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1964 年 2 巻 1 号 p. 34-45

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In 24 healthy volunteer males, changes of pulmonary airway resistance were measured in the following sequence of inhalation ; 1) after short term inhalation of hydrogen peroxide aerosols in two groups of 4.6μ and 1.8μ of their count median diameter, 2) sulfur dioxide (1-60 ppm), 3) mixture aerosols of hydrogen peroxide and sulfur dioxide, 4) bronchodilator, 5) the mixture aerosols of the same to 3), and their effects were compared with the preexperi-mental control level. A synergistic increase of the response was observed by the mixture aerosols which were recognized as sulfuric acid mist. Difference of the particle size resulted in different response to the respiratory tracts.
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© National Institute of Occupational Safety and Health
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