EFFECT OF NITROGLYCOL ON ACTOMYOSIN
1971 年 9 巻 1-2 号 p. 26-35
詳細
1971 年 9 巻 1-2 号 p. 26-35
Marked effects of nitroglycol on superprecipitation of actomyosin and on the initial burst of ATP decomposition by actomyosin were observed in vitro experiments. Instantly after incubating actomyosin with 0.22000 μM of nitroglycol, both super- precipitation and the initial burst were suppressed, while after 24 hours' standing at 0°C, they were strengthened reversely. The reverse effect of nitroglycol on actomyosin was explained as being due to the structural changes of actomyosin in respect of α-helix content. In a previous study, we have found out that actomyosin prepared from poisoned rabbits differed from normal one. Probably actomyosin and thus muscle fiber also of poisoned animals may be in disturbed states in respect of its structure and function.
