EXPERIMENTAL STUDY OF METHYL IODIDE POISONING (II)

抄録

This study was performed for finding out early diagonosis methods of methyl iodide or methyl bromide intoxication. Methyl iodide introduced into living organism was found in the brain, especially in the cerebral cortex, and in the liver and kidney. Gait disturbance which is one of the serious effects of methyl iodide on the nervous system seemed to be an representation of susceptibility increase of the organism agaist d-tubocurarine as reported previously. At this intoxication state, a disturbed pattern of lipid metabolism in brain tissues was observed similarly as the metabolic distur- bance of energy rich phosphate compounds reported already. Previously, we have found out an abnormal increase of serum lipid in poisoned animals. This finding was also ascertained by examining men exposed to methyl iodide or methyl bromide. Present address, Japan Industrial Safety Association, 5-35-4, Shiba, Minato-ku, Tokyo.