Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Immunological Studies on Opportunistic Infection and the Development of Adult T-cell Leukemia
Takayoshi TASHIROTohru YAMASAKIHiroyuki NAGAIHiroshi KIKUCHIMasaru NASU
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1992 年 31 巻 9 号 p. 1132-1136

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Three patients with opportunistic infection preceding adult T-cell leukemia (ATL) are presented : a 66-year-old woman with cryptococcosis and Pneumocystis carinii pneumonia, a 46-year-old man with Pneumocystis carinii pneumonia, and a 55-year-old woman with cryptococcosis. Although, at the first examination, the first two had smoldering type ATL and the third case was an HTLV-I carrier, all three developed overt ATL 14-16 months after the onset of opportunistic infection. It is considered that there is immune suppression already present in HTLV-I carriers and in patients with smoldering ATL, and opportunistic infection is predictive of the development of ATL.
(Internal Medicine 31 : 1132-1136, 1992)
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© The Japanese Society of Internal Medicine
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