口腔からの Staphylococcus aureus の分離と抗菌薬感受性

抄録

Fifty-eight strains of Staphylococcus aureus were isolated from saliva and dental plaques of 66 healthy students and staff members of Iwate Medical University. The coagulase types, and productions of hemolysin, staphylococcal enterotoxins, toxic shock syndrome toxin-1, and β-lactamase, and susceptibility to 22 antimicrobial agents were investigated using these strains.

S. aureus was isolated from the saliva of 68.1% of the 66 subjects and from dental plaque of 19.6%. Types Ⅶ coagulase was predominant (25.8%). Both α and δ types of hemolysin were produced in 100% of the isolates. Staphylococcal enterotoxins were produced in 39.6% of the 58 strains, and type A was predominant. Penicillinase was produced in 75.8%. In the susceptibility test, the isolated strains were resistant to AMPC, CP, CZX, EM, RKM and PCG, whose minimum inhibitory concentrations were ≧ 16μg/ml.