澱粉科学
Online ISSN : 1884-488X
Print ISSN : 0021-5406
ISSN-L : 0021-5406
アミラーゼインヒビター"TAI"について
並木 信重郎神郡 邦男長手 尊俊杉田 和彦原 寛森 恵津子大村 貞文大関 正弘
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1980 年 27 巻 2 号 p. 107-113

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TAI-A and TAI-B showed inhibitory activities against sucrase, maltase and isomaltase isolated from hog small intestine according to the method of Dahlqvist. TAI suppressed the increase of the blood glucose level of fasting mice administered with maltose. TAI suppressed the increase of the blood glucose level and the secretion of insulin of rats which were fasted and then forced-fed cooked corn starch, because of the inhibition against the starch digestion in the small intestine. The suppression of the increase in the body weight was observed in the 3 months toxicity test on the groups which were given diet containing 1.82 and 908 GIU/g of TAI, respectively . Hematological and histopathological examinations did not reveal any remarkable difference among all the experimental animals. TAI inhibited the growth of some anaerobic bacteria belonging to Clostridia, but did not show any inhibitory activity against other anaerobic bacteria. TAI and maltotriose showed an synergistic effect on the antibacterial activity.

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© 日本応用糖質科学会
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