The Complications Accompanied by Weight Gain Subsequent to Smoking Cessation in Japanese Males

抄録

Objectives To investigate tendencies in body weight and several laboratory data including plasma glucose and plasma lipids subsequent to smoking cessation.
Design A case-control study.
Setting and Participants Subjects consisted of 240 consecutive males 6 to 18 months after smoking cessation, who consulted our institute for health screening between October 2004 and February 2005.
Measurement and Results We compared quantitative changes in data pre and post smoking cessation in quitters with annual data in current smokers. The variables examined were: body weight (BW), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting plasma glucose (FPG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglyceride (TG), uric acid (UA), aspartate acid aminotransferase (AST), and alanine aminotransferase (ALT) . Positive changes in BW, SBP, DBP, FPG, TC, HDL-C, LDL-C, UA, and AST for quitters were significantly higher than those for current smokers. However, only a positive change in HDL-C for the group of the lowest change in body weight by quartile, which included all of the patients showing almost weight loss, was significantly more than one for current smoker. In opposition, positive changes in all variables for quitters who gained 1.8 kg or more were significantly higher than those in current smokers.
Conclusions We consider that physicians should provide sufficient social guidance including diet and exercise advice to suppress weight gain subsequent to smoking cessation.