Antioxidant Activity of Hydroxyflavonoids

Miyuki Furusawa; Toshiyuki Tanaka; Tetsuro Ito; Asami Nishikawa; Naomi Yamazaki; Ken-ichi Nakaya; Nobuyasu Matsuura; Hironori Tsuchiya; Motohiko Nagayama; Munekazu Iinuma

doi:10.1248/jhs.51.376

RESEARCH LETTERS

Antioxidant Activity of Hydroxyflavonoids

Miyuki Furusawa, Toshiyuki Tanaka, Tetsuro Ito, Asami Nishikawa, Naomi Yamazaki, Ken-ichi Nakaya, Nobuyasu Matsuura, Hironori Tsuchiya, Motohiko Nagayama, Munekazu Iinuma

Author information

Miyuki Furusawa
Gifu Prefectural Institute of Health and Environmental Sciences
Toshiyuki Tanaka
Gifu Prefectural Institute of Health and Environmental Sciences
Tetsuro Ito
Gifu Prefectural Institute of Health and Environmental Sciences
Asami Nishikawa
Gifu Prefectural Institute of Health and Environmental Sciences
Gifu Pharmaceutical University
Naomi Yamazaki
Gifu Prefectural Institute of Health and Environmental Sciences
Gifu Pharmaceutical University
Ken-ichi Nakaya
Gifu Prefectural Institute of Health and Environmental Sciences
Nobuyasu Matsuura
Faculty of Science, Okayama University of Science
Hironori Tsuchiya
Asahi University School of Dentistry
Motohiko Nagayama
Asahi University School of Dentistry
Munekazu Iinuma
Gifu Pharmaceutical University

Keywords: hydoxyflavonoid, antioxidant activity, structure-activity relation ship

JOURNAL FREE ACCESS

2005 Volume 51 Issue 3 Pages 376-378

DOI https://doi.org/10.1248/jhs.51.376

Details

Abstract

The antioxidant activity of 28 natural and synthetic hydroxyflavonoids was estimated through the 1,1-diphenyl-2-picrylhyrazyl (DPPH) radical, superoxide scavenging activities and lipid peroxidation inhibition. The result showed the hydroxylation pattern had close relationship with the appearance of activities.

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