Abstract
The effects of some fibers on the in vitro and in situ rat small intestinal absorption of cadmium were studied. The fibers, such as cellulose, pectin, glucomannan, lignin, sodium alginate (Na alginate), and sodium carboxymethylcellulose (Na CMC), tended to depress the intestinal absorption of cadmium. The depressive effects of lignin, Na alginate, and Na CMC on the absorption of cadmium were much greater than those of cellulose, pectin, and glucomannan. In addition, the effects of these fibers on the in vitro intestinal transport of cadmium were examined in the presence of L-cysteine or L-histidine, a stimulator of transport of the metal. Lignin and Na CMC depressed the stimulation of transport of cadmium by L-histidine.
