The Determination of Volatile Halogenated Organic Compounds in Drugs

Abstract

Volatile halogenated organic compounds in tonics, waters for injection and infusion preparations were determined by the headspace gaschromatograph method. Chloroform and 1, 1, 1-trichloroethane were detected in tonics. The highest concentration of chloroform was 0.011 mg/l and that of 1, 1, 1-trichloroethane was 0.010 mg/l. The contents of these compounds in water for injection and infusion preparations were very low.