jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Enhancing effects of drug concentration in tissues using the combined therapy of Cefotiam hexetil hydrochloride and Serrapeptase
Mamoru TSUKUDAKeiko ITOYasuhiro ARAIAkira KUBOTA
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Keywords: Cefotiam hexetil
JOURNAL FREE ACCESS

1993 Volume 39 Issue 4 Pages 577-580

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Abstract
This study investigates the concentration of Cefotiam hexetil hydrochloride (CTM-HE) found in blood and excised tissues when CTM-HE was administered during surgery both with and without the prolonged administration of Scrrapeptase, an anti-inflammatory enzyme. The results were as follows:
1) The concentration of CTM was found to be higher in the combined CTM-HE and Serrapeptase group than in the CTM-HE only group.
2) The combined therapy of CTM-HE and Serrapeptase improves the effectiveness of CTM-HE in inflammatory diseases of the head and neck regions.
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