Abstract
This study investigates the concentration of Cefotiam hexetil hydrochloride (CTM-HE) found in blood and excised tissues when CTM-HE was administered during surgery both with and without the prolonged administration of Scrrapeptase, an anti-inflammatory enzyme. The results were as follows:
1) The concentration of CTM was found to be higher in the combined CTM-HE and Serrapeptase group than in the CTM-HE only group.
2) The combined therapy of CTM-HE and Serrapeptase improves the effectiveness of CTM-HE in inflammatory diseases of the head and neck regions.