All issues
Volume 39, Issue 4
Displaying 1-12 of 12 articles from this issue
- |<
- <
- 1
- >
- >|
-
Katsuya YAMAGUCHI1993 Volume 39 Issue 4 Pages 533-541
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSEighteen pigmented rabbits were used for this study. Following obliteration of the endolymphatic sac, the vestibular function was examined by caloric and rotatory tests, and the fine structure of the crista ampullaris of the horizontal semicircular canal and macula utriculi was observed by transmission electron microscopy. The caloric response was reduced in 7 cases. No change was detected by the rotatory test in any of the cases. Spontaneous deviation of the head was observed in one case. Vacuolization, swelling or disruption of mitochondria were found in the hair cells and suppotring cells of the macula utriculi in 14 cases. These same structural changes were found in the hair cells and supporting cells of the crista ampullaris in 9 cases, which also showed a higher rate of hypoactive caloric responses than the other cases. The degeneration of the macula utriculi and crista ampullaris always occured simultaneously with endolymphatic hydrops.View full abstractDownload PDF (21933K) -
Shizuo KOJA, Tetsuo ITOKAZU, Satoshi KAMIYA, Hiroaki ESU1993 Volume 39 Issue 4 Pages 542-546
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSOne hundred and four patients with oral carcinoma treated at the Department of Otorhinolaryngology, University of the Ryukyus Faculty of Medicine from 1974 to 1985 were reviewed. In the incidence of patients with carcinoma of the floor of the mouth, advanced neck lymphnode metastases were observed most frequently. For such patients, chemotherapy and radiotherapy were the treatments of choice. The crude five year survival rates were 50% for carcinoma of the buccal mucosa, 45% for carcinoma of the tongue, 20% for carcinoma of the hard palate and 11% for carcinoma of the floor of the mouth.View full abstractDownload PDF (7506K) -
Eiken MATSUDA, Yuichi TAKEUCHI, Takurou ENOMOTO, Toshitsugu TANIMOTO, ...1993 Volume 39 Issue 4 Pages 547-550
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA case of deep neck infection with perforated duodenal ulcer is reported. Owing to a delay in timely surgical intervention, a deep neck infection secondary to fulminating peritonsillitis resulted in severe mediastinitis. Concomitantly, a duodenal ulcer which progressed to duodenal perforation appeared in this patient. The ulcer might be attributed to the administration of steroids, antibiotics, analgesics and antipyretics, or to stress related to the patient's condition. This case emphasized to us that in the treatment of such conditions, it is imperative that accurate diagnostic information be obtained promptly and appropriate treatment initiated immediately. It is vital to recognize that drug-induced or stress related digestive duct ulcers are not rare, and require prompt attention.View full abstractDownload PDF (8704K) -
Takashi KONDO, Yasuhisa HASEGAWA1993 Volume 39 Issue 4 Pages 551-558
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe investigated the unknown primary cancers in 347 cases during the years 1983 to 1987 using the Annual of the Pathological Autopsy Cases in Japan. We analyzed cancer diagnoses using several parameters including: autopsy, medical specialty department, double-site cases, therapeutic approach and the characteristics of the primary site as reflected in the metastatic sites. We also studied the ratio of the cases of the primary sites confirmed by autopsy to the unconfirmed cases. In cases in which the primary site was the head and neck, we studied their remote metastatic sites.View full abstractDownload PDF (14225K) -
Yuuichi TAKEUCHI, Eiken MATSUDA, Seiko IKOMA, Yoshimitsu HASHIMOTO, Ke ...1993 Volume 39 Issue 4 Pages 559-563
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSTwo cases of juvenile laryngeal papilloma are reported. Case 1 was a 4-year-old girl who complained of hoarseness in September, 1987. She was treated by surgical removal of the tumor and CO, laser under laryngomicroscopy and postoperative 5-FU nebulizer. The histological specimen showed hyperkeratosis, disturbance of the basement membrane and mild epithelial atypia. Treatment was repeated 8 times for 3 years. After the last treatment no evidence of recurrence was seen after one and one-half years and the patient's voice remains good. Case 2 was a 3-year-old boy who complained of hoarseness in June, 1991. His tumor was surgically excised. The histological specimen showed hyperkeratosis. Six months after the last treatment, no evidence of recurrence was noted and the patient's voice remains good. Some of the problems common to juvenile laryngeal papilloma are discussed.View full abstractDownload PDF (9748K) -
Masahiro KAWAIDA, Hiroyuki FUKUDA, Naoyuki KOHNO1993 Volume 39 Issue 4 Pages 564-569
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSTreatment of laryngeal lesions with laryngomicrosurgical technique by using side-opened direct laryngoscope and electrocoagulator is introduced. We designed a side-opened direct laryngoscope which is characterized by an opening from the anterior tip to the posterior end of the right side. The side-opened direct laryngoscope enabled easy insertion of the extra length electrode (20.5cm) to perform hemostasis by electrocoagulation through the right side opening. In this paper, the method is demonstrated with a clinical case report and discussed from the view point of the surgical manipulations of electrocoagulation that may influence postoperative results.View full abstractDownload PDF (14393K) -
Nobuharu TAGASHIRA, Mamoru SUZUKI, Katsuhiro HIRAKAWA, Yasuo HARADA, S ...1993 Volume 39 Issue 4 Pages 570-573
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSOral ofloxacin (OFLX) was compared to injectable cephem or penicillin for its effectiveness in preventing infections following middle ear surgery. The following results were obtained.
1. Postoperative infections were prevented successfully in all 10 cases treated orally with OFLX.
2. Cephem or penicillin injections prevented postoperative infections in 86% of all ears (including ears that had been infected before surgery and ears that had been free of infection before surgery).
3. Cephem or penicillin injections prevented postoperative infections in all ears that had been free of infection before surgery.
4. In ears that had been free of infection before surgery, the postoperative prophylactic effects did not differ between the oral treatment group and the injection group.
5. No adverse reactions or laboratory abnormalities were found in either group.
These results indicate that oral OFLX treatment is highly effective in preventing postoperative infections following middle ear surgery on uninfected ears. Considering its efficacy, safety, low cost, the reduced burden on medical workers and the reduced stress for patients, OFLX may replace conventional injections in preventing postoperative infections.View full abstractDownload PDF (6539K) -
Nobukazu YAMAMOTO, Tetsuo ISHII1993 Volume 39 Issue 4 Pages 574-576
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSEthyl loflazepate was administered orally to 11 patients with tinnitus (in combination with vitamin B12 in 8 patients and alone in 3). This drug proved effective in 7 patients (64%), particularly in 4 of 5patients without organic disease (80%). In the patients who responded to this drug, the effects appeared within 2 weeks after the initiation of administration. Slight drowsiness following administration was observed in 4 patients (36%) but this side effect presented no problems to the continuation of drug administration. These results suggest that ethyl loflazepate may be useful in the initial treatment of patients with tinnitus.View full abstractDownload PDF (5196K) -
Mamoru TSUKUDA, Keiko ITO, Yasuhiro ARAI, Akira KUBOTA1993 Volume 39 Issue 4 Pages 577-580
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThis study investigates the concentration of Cefotiam hexetil hydrochloride (CTM-HE) found in blood and excised tissues when CTM-HE was administered during surgery both with and without the prolonged administration of Scrrapeptase, an anti-inflammatory enzyme. The results were as follows:
1) The concentration of CTM was found to be higher in the combined CTM-HE and Serrapeptase group than in the CTM-HE only group.
2) The combined therapy of CTM-HE and Serrapeptase improves the effectiveness of CTM-HE in inflammatory diseases of the head and neck regions.View full abstractDownload PDF (6597K) -
Tadatsugu MAEYAMA, Norifumi MAEHARA, Takemoto SHIN1993 Volume 39 Issue 4 Pages 581-588
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe Chinese (Kampo) medicine, Syohseiryu-toh, has been shown to improve such symptoms as suppuration, inflammation and allergic reaction. This study evaluates the effectiveness of this medicine for the treatment of chronic sinusitis. The therapeutic effect was rated very good in 5%, moderate in 50%, and slight in 25% of the cases. Rhinorrhea, nasal obstruction and postnasal discharge were highly improved. The long term (7-12 months) administration of medication was more effective than short term (3-6 months) administration. No side effects were observed in any of the patients. Syohseiryu-toh is useful for treatment of patients with chronic sinusitis.View full abstractDownload PDF (11400K) -
Shunkichi BABA, Naoya MIYAMOTO, Shinichiro YAMAMOTO, Soichiro NAGATA, ...1993 Volume 39 Issue 4 Pages 589-604
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSNorfloxacin (NFLX; 50mg tablets) was administered to 97 infants and children able to tolerate the medication at a dose of 6-12mg/kg per day, given on 3 separate occasions within 7 days. The patient sample included 52 cases of otitis media and 45 cases of sinusitis. In cases demonstrating improvement during observation on the 7th day, doses were continued through the 14th day.
Excluding those patients who did not complete the treatment regimen, the efficacy of NFLX in 46 cases of otitis media and 43 cases of sinusitis was 78% (36/46) and 72% (31/43), respectively.
With respect to elimination of isolated bacteria, 82 of 101 strains were eliminated for an elimination ratio of 81%.
No adverse effects were reported. Increased platelets was found in one case.
Based on the above results, NFLX achieves excellent clinical results in the treatment of pediatric otitis media and sinusitis. It is particularly effective in such cases caused by H. influenzae, M.(B) catarrhalis, P. aeriginosa and similar bacteria which have low susceptibility to β-lactam drugs.View full abstractDownload PDF (24760K) -
Naoya MIYAMOTO, Shunkichi BABA, Takehiro KOBAYASHI, Shinji KATO, Haruo ...1993 Volume 39 Issue 4 Pages 605-614
Published: July 20, 1993
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA multicenter open study was carried out to evaluate the clinical efficacy and safety of orally administered ciprofloxacin (100mg-200mg t. i. d.) in the treatment of suppurative otitis media and sinusitis. The following results were obtained.
1) Clinical efficacy was evaluated by the physicians in charge in 39 cases (sex: male 12, female 27; mean age: 46.4 years old; mean duration of administration: 9.0 days; diagnosis: suppurative otitis media 17, sinusitis 22). The rates of effectiveness were 82% (32/39) for all cases, 77% (13/17) for suppurative otitis media and 86% (19/22) for sinusitis.
2) As causative organisms, 21 strains were isolated from 20 cases before treatment. The bacteriologic eradication rate was 82% (14/17).
3) No side effects were reported.
4) Tissue (maxillary sinus mucous membrane, etc.) and serum concentrations of ciprofloxacin were evaluated. In maxillary sinus mucous membrane, the mean concentrations were 0.40μg/g and in serum the mean concentrations were 0.29μg/ml at 120 minutes after 200mg oral administration.
From these results, oral ciprofloxacin is considered to be very useful for the treatment of suppurative otitis media and sinusitis.View full abstractDownload PDF (16939K)
- |<
- <
- 1
- >
- >|