日本耳鼻咽喉科学会会報
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
前庭膜迷路に対する Actinomycete Streptomyces Punicens (Viomycin) の作用機序に関する電子顕微鏡的研究
竹中 文一郎浜 広信鈴木 政昭川本 智平山 方哉
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1967 年 70 巻 6 号 p. 1124-1127

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抄録
This experiment was performed as a part of the series of the electron microscopic studies on vestibular apparatus.
(1) The cells of ampullae of the labyrinth which were damaged with Viomycin in various doses were revealed electron microscopically.
(2) The cell surface and the apical cytoplasm of ampullae of the labyrinth were damaged.
(3) The dense body and multivesicular body extremely resembling lysosome were observed.
(4) There was evidence morphologically that the onset of cell damage by Viomycin seemed to begin at the cell surface such as effect of Strepto. mycin or Kanamycin.
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