Abstract
The effects of black soybean extract on the glucose metabolism.
Objective : To investigate the effects of black soybean extract (SE) on the glucose metabolism.
Materials & Methods : The effects of SE on the activity of α-glucosidase were examined in vitro. The effects of the simultaneous SE ingestion on the 75 g oral sucrose and glucose tolerance tests and those of long-term (4 weeks) SE ingestion for young healthy women were then examined.
Results : SE inhibited the α-glucosidase activity in vitro. The simultaneous ingestion of SE ameliorated the rise in blood glucose levels induced by 75 g of sucrose and glucose during the tolerance tests. The long-term ingestion of SE improved the glucose metabolism, increased the serum biological antioxidant potential, and decreased the serum reactive oxygen metabolites.
Conclusion : In the present study, the ingestion of SE improved the glucose tolerance and increased the antioxidant status. The daily ingestion of SE will be useful for the prevention of glucose intolerance and diabetes mellitus.