Effects of pre-germinated brown rice (PGBR) on postprandial blood glucose and insulin concentrations were compared with white rice (WR) in 16 (8 women and 8 men) subjects with hyperglycemia. We investigated the time course of postprandial blood glucose and insulin concentrations after ingesting PGBR or WR. The study was a randomized, cross-over design in which subjects participated in two separate 3-hour meal tolerance test. The tolerance tests were spaced more than 7 days apart for each subject. All the rice samples contained 50 g of available carbohydrates. The previous day the subjects ate the assigned dinner by 9:00 pm and then were allowed only water until the examination. The next morning, they ingested each test rice sample with 150ml of water in 5-10 min. Blood was sampled from the cubital fossa vein at 0, 30, 60, 90,120 and ISOmin after the ingestion. The postprandial blood glucose after ingesting PGBR was lower than WR, and the values of 60, 90,180 min were significantly lower (p<0.05). The incremental area under the curve (IAUC) of blood glucose concentrations for 180 min after the administration of PGBR was lower than that of WR (p<0.05). The postprandial blood insulin after ingesting PGBR was lower than WR, but not significant. IAUC of blood insulin concentrations of PGBR is tended lower compared with that of WR (p=0.07). These results suggest that intake of PGBR instead of WR is effective for the control of postprandial blood glucose concentration without increasing the insulin secretion in subjects with hyperglycemia.
