抄録
We report a 4-year-old girl with nephrotic syndrome who was diagnosed as IgA nephropathy. Four years old girl came to the hospital in chief complaint for anasarca, with proteinuria and frank haematuria.
Renal biopsy revealed diffuse mesangial hypercellularity, with focal endotherial hypercellularity, cellular crescents, and mesangial IgA and C3 deposits, consistent with IgA nephropathy. Predonisolone was administered intravenously (2 mg/kg/day) with anticoagulant and antiplatelet agents. Her symptoms regressed but still her proteinuria persisted. Then immunosuppressive therapy (cyclosporine) was added to her treatment as her bone material density was very low. After 5 months, her urinalysis became normal and her renal function kept normal. The optimum level of cyclosporine for the treatment with IgA nephropathy was relatively low (30∼90 ng/ml). Here we reported the diagnosis of IgA nephropathy in a young girl with nephrotic syndrome who was treated with steroid, anticoagulant, antiplatelet and immunosuppressive therapy.
