抄録
The change in hormonal and immune state of university male students who were engaged in his graduation examination was investigated as a behavioral medicine study targeting on chronic stress. With regard to biomarkers of human hormonal and immune state, salivary secretory substances, Immunoglobulin A (IgA), Cortisol, Chromogranin (CgA), and dehydroepiandrosterone (DHEA), were assayed about a week before and 2 weeks after the day of oral defense of the graduation examination for 20 male students. As a result, the salivary immune substance, IgA, significantly decreased (p<0.001), while other biomarkers showed no significant change. In conclusion, it was suggested that IgA can be a promising candidate for a chronic stress marker.
