Various colors are used for things that we use in daily life. Color combinations are important for design, and have a great influence on image or human kansei. The purpose of this study is to model the relation between two-color combinations and human emotions, and to apply it to the design support. In this paper, we propose emotion two-color combination models generated by the quantification theory type I. First, harmonized two-color combinations are generated by color harmony theories, and these color combinations are evaluated by the semantic differential method in order to clarify the relation between two-color combinations and basic emotions. Next, statistical models concerning emotions and color combinations are generated by analyzing acquired data using quantification theory type I. We applied these models to a uniform color combination system. Related models of image words of sport and emotions were generated, and these were combined with emotion two-color combination models. Finally, we constructed a simplified uniform color combination system, and confirmed effectiveness of models.