Abstract
A cross-breed male dog had chronic bacterial bilateral otitis externa and was treated with antimicrobial drugs. Drainage and erosion were observed in both external ears. The drainage fluid contained neutrophils and rod-shaped bacteria and consequently bacterial culture and antimicrobial susceptibility testing were performed. Multidrug-resistant Pseudomonas aeruginosa was isolated, but the bacteria were susceptible to fosfomycin and ofloxacin. Thus, following washing of both external ears, the dog was treated by administering fosfomycin orally and applying ofloxacin ointment topically for 4 weeks. The dog was cured and no recurrence has been observed to date. It is important for bacterial culture and antimicrobial susceptibility testing to protect of multidrug-resistant bacterial otitis externa.