関西医科大学雑誌
Online ISSN : 2185-3851
Print ISSN : 0022-8400
ISSN-L : 0022-8400
腸滑平筋内セロイド様色素の出現並に腸粘膜黒色症を伴なつた胃癌の一剖検例
金澤 浩吉近藤 直萩原 辰治
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1969 年 21 巻 2 号 p. 76-82

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This patient died from gastric cancer.
However, in addition to gastri c cancer, our autopsy revealed a combined deposit of ceroid pigment and melanosis pigment, and fat necrosis of the pancreas. It is an infrequent disorder that a deposit of ceroid pigment occurs in the smooth muscle of the small intestine and a deposit of melanosis pigment in the mucosa of the large intestine. According to Braunstein, a ceroid pigment deposition was observed in the smooth muscle of the small intestine in 22 out of the 36 adult cases with chronic pancreatits which caused a tocopherol deficiency. On the other hand, ceroid pigment in the smooth muscle of the small intestine was observed by Blanc et. al. in autopsy cases of children with cystic fibrosis of the pancreas and congenital biliary atresia, and a similar case was reported by Kerner and Goldbloom.
The most important factor of a ceroid pigment deposition in the smooth muscle of the small intestine seems to be a deficiency of tocophrol caused by malabsorption of fats.
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