藥物その他によるアレルギーにおける白血球の関与についての研究特に臼血球輩白感作ウオリ,ン凝集反応・および白血球を用いるCytotoxic Testについて

第四篇-アレルギー性疾患,とくに気管支喘息におけるCytotoxic Activity Testを用いるアレルゲンの検出法

抄録

Both cytotoxic and cytolytic activities in the presence of allergens in sera samples obtained from bronchial asthma patients were studied by means of the dye-exclusion technique. The results obtained were as follows:
1) The sera showed high cytotoxic activity brou ght on by the addition of the responsible allergens.
2) The leucocyte counts were markedly decreased in vitro by the addition of the responsible allergens.
These resu lts suggest that bronchial asthma patients not only have the well-known skin sensitizing antibodies, but also seral antibodies as well.