Journal of Occupational Health
Online ISSN : 1348-9585
Print ISSN : 1341-9145
ISSN-L : 1341-9145
Original Articles
A longitudinal study of working hours and chronic kidney disease in healthy workers: The Kangbuk Samsung Health Study
Yesung LeeEunhye SeoEunchan MunWoncheol Lee
Author information
JOURNAL OPEN ACCESS

2021 Volume 63 Issue 1 Article ID: e12266

Details
Abstract

Objectives: Long working hours are linked to an increased risk of exposure to work safety hazards that threaten the health of workers. To date, only a few cross-sectional studies regarding the relationship between working characteristics, such as over-workload and chronic kidney disease (CKD) have been reported. Therefore, in this longitudinal study, we aimed to examine the direct relationship between long working hours and the incidence of CKD.

Methods: We included 97 856 participants without CKD in the Kangbuk Samsung Health Study. Using a self-report questionnaire, we evaluated weekly working hours, which were categorized into 35-40, 41-52, and >52 hours. CKD was defined as estimated glomerular filtration rate <60 mL/min/1.73 m2. Hazard ratios (HRs) and 95% confidence intervals (CIs) for incident CKD were estimated using Cox proportional hazards regression analyses with weekly working 35-40 hours as the reference.

Results: During a median follow-up of 4.0 years, 185 participants developed incident CKD (incidence density, 4.83 per 104 person-years). Multivariable-adjusted HRs (95% CI) of incident CKD for weekly working >52 hours compared with working 35-40 hours were 1.99 (1.22-3.25). In subgroup analyses, the significant association between working >52 hours and incident CKD was consistently observed in groups of age ≥40 years, men, and obesity with no interaction.

Conclusions: Our large-scale cohort study of young- to middle-aged men and women demonstrated a significant association between long working hours and an increased risk of incident CKD.

Content from these authors

This article cannot obtain the latest cited-by information.

© 2021 The Authors. Journal of Occupational Health published by John Wiley & Sons Australia, Ltd on behalf of The Japan Society for Occupational Health

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
https://creativecommons.org/licenses/by-nc-nd/4.0/
Previous article Next article
feedback
Top