抄録
In a previous paper (M. Shimizu: J. Mol. Evol. 18 (1982) 297), it was discussed by using the CPK molecular model that a pocket on a complex of four nucleotides (C4N), namely three anticodon bases and a discriminator base, can recognize the cognate proteineous amino acid by a lock and key relationship. An experimental support for this picture is given here. Some C4Ns have been detected by using an ultraviolet difference absorbance method and their high specificity to the amino acids has been shown, explicitly giving the binding constants among them.
