一般論文
加熱によるα-シクロデキストリン－ポリエチレングリコール包接化合物形成の検討
2000 年 60 巻 2 号 p. 139-147
詳細
2000 年 60 巻 2 号 p. 139-147
α-Cyclodextrin (α-CD) crystals were heated with polyethylene glycol 4000 (PEG4000) in a sealed glass ampule. Inclusion formation was studied as a function of heating temperature, heating time, and water content of α-CD by X-ray diffraction and thermogravimetry-differential thermal analysis. PEG4000 molecules were included in the α-CD cavity by heating, and the formation of an inclusion compound was accelerated by heating above 90°C. A compressed disk of α-CD crystals was prepared and soaked in molten PEG4000 at 90°C. The results indicate that PEG molecules penetrated into α-CD crystals, and the inclusion compound formation was proceeded as solid state reaction.
